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Collagen Renewal Serum for Mature Skin

Collagen Renewal Serum for Mature Skin

 (11168 Reviews)

Peptide-Powered Collagen Renewal for 40+ Skin

As skin matures, its natural collagen production gradually declines, which can affect the look of firmness, fullness, and elasticity. This targeted renewal serum features four complementary peptides designed to work together to support your skin's collagen foundation and restore a more plump, firm-looking appearance.

Four Peptides. One Powerful Renewal Routine.

• Designed for 40+ Skin: Created with the changing needs of mature skin in mind, especially skin that looks less firm or resilient.
• 4-Peptide Formula: Four peptides work together as a targeted approach to collagen-focused skincare.
• Supports Collagen: Helps support the skin's natural collagen-related processes for a stronger-looking skin foundation.
• Plumper-Looking Skin: Helps restore the appearance of fullness for a more supple, youthful-looking complexion.
• Firmer Appearance: Supports the look of improved firmness and skin resilience.
• Strengthens the Skin's Foundation: Designed to focus on the underlying appearance of skin structure rather than simply providing surface hydration.

Your Skin, With More Bounce

Apply a few drops to clean skin and gently massage until absorbed. Follow with your favorite moisturizer. Use consistently as part of your daily skincare routine for mature skin.

Four peptides working together to support collagen, firmness, fullness, and your skin's natural foundation.

Regular price $42.95
Regular price $42.95 Sale price $47.95
SAVE 10% Sold out

BUNDLE & SAVE

Collagen Renewal Serum for Mature Skin

Collagen Renewal Serum for Mature Skin

Regular price $42.95
Regular price $42.95 Sale price $47.95
SAVE 10% Sold out

Shipping & Returns

• Free US Shipping on all orders over $50
• 100-Day Guarantee: Try it risk-free for 100 days from delivery
• Zero Return Fees: Return shipping is on us

Awards

🏆 Winner - Best Firming Serum in Cosmopolitan's Clean Beauty Awards

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I love waking up in the morning after using this the night before.
My face always feels so plump and my eye bags seem to disappear...

Jenna R.

Customer since 2024

The serum’s cobalt-blue color comes from copper peptides, not artificial dyes.

PEPTIDE SQUAD

COLLAGEN RENEWAL SERUM

Meticulously formulated with all four classes of science-backed peptides

    DEEP HYDRATION 

    We've boosted the naturally hydrating properties of peptides with a blend of hyaluronic acid, ceramides, and jojoba oil, enhancing your skin to feel more plump, soft and rejuvenated.

    Peptide blend product

    Comprehensive anti-aging peptide blend

    • Copper tripeptide-1 (GHK-Cu)
    • Matrixyl 3000
    • Argireline
    • Rice peptides

    SKIN CARE BENEFITS

    Boosts collagen production.

    Reduces fine lines and wrinkles.

    Firms up skin.

    Deep hydration.

    SKIN CARE BENEFITS

    HOW TO USE

    • Apply serum to the face, neck, and chest.
    • Massage product in until it is absorbed.
    • Follow with a gentle moisturizer to lock in the serum.
    • For AM and/or PM.

    Peptide Squad Serum

     A Closer Look 

    Join thousands of happy customers and experience the MAELOVE difference in your skincare routine.

    ✦ The only serum with all four categories of science-backed wrinkle-fighting peptides

    THE 4-PEPTIDE COMPLEX (Copper Tripeptide-1, Matrixyl 3000, Argireline, Rice Peptides)

    • Each peptide tackles a different cause of aging, and together they rebuild collagen, prevent breakdown, relax expression lines, and restore firmness.
    • This is the advantage of combining peptides: faster, more comprehensive results than any single peptide can deliver.

    CALM & SKIN BARRIER SUPPORT (Niacinamide, Panthenol, Ceramides, Turmeric, Jojoba Oil)

    • Fortifies your skin's protective barrier, which weakens with age.
    • This blend reduces the appearance of redness while minimizing potential irritation.

    HYDRATION BOOST (Hyaluronic Acid, Glycerin, Rice Peptides)

    • Draws moisture into the skin for a smooth, plump appearance.
    • This lightweight base is what ensures the serum absorbs instantly without leaving a sticky or tacky residue.

    Our Director of Research, Dr. Sunbin Song (MIT PhD and former NIH researcher), hosts educational webinars at top dermatology schools, helping to bridge clinical science with the skincare industry.

    1,200+

    Dermatology Residents

    50+

    Top Residency Programs

    3+

    Years Running

    Obsessively formulated

    Skincare shouldn’t force a compromise. “Gentle” shouldn’t mean weak, and “high-strength” shouldn’t mean harsh.

    We spent years figuring out how to deliver both—pairing potent actives with barrier-supporting and anti-inflammatory ingredients.

    The result is a simple promise: effective formulas that your skin can tolerate and enjoy for the long run.

    Meet your skin team

    Skincare formulation expert

     FAQ 

    Full ingredient list

    All Maelove products are tested for sensitive skin (Human Repeat Insult Patch Testing conducted at third-party labs), made in the US, vegan, cruelty-free, non-comedogenic, gluten-free, and free of parabens, phthalates, dyes, and artificial fragrances. We don't use ingredients that are banned in the EU or in the USA.

    Aqua (Water), Glycerin, Propanediol, Caprylyl Glycol, Niacinamide, Panthenol (D), Simmondsia Chinensis (Jojoba) Seed Oil, Copper Tripeptide-1, Ceramide EOP, Ceramide NP, Acetyl Hexapeptide-8, Ceramide AP, Allantoin, Sodium Hyaluronate (L), Palmitoyl Tripeptide-1, Palmitoyl Tetrapeptide-7, Hydrolyzed Rice Protein, Aloe Barbadensis Flower Extract, Bisabolol (L-alpha), Curcuma Longa (Turmeric) Root Extract, Camellia Sinensis (Green Tea) Leaf Extract, Melia Azadirachta (Neem) Leaf Extract, Melia Azadirachta (Neem) Flower Extract, Hamamelis Virginiana (Witch Hazel) Water, Chondrus Crispus (Carrageenan) Extract, Glycine, Pullulan, Sodium Lactate, Coccinia Indica Fruit Extract, Cholesterol, Carbomer, Solanum Melongena (Eggplant) Fruit Extract, Dimethicone, Butylene Glycol, Polysorbate 20, Sodium Gluconate, Madecassoside, Hydrolyzed Gardenia Florida Extract, Phytosphingosine, Corallina Officinalis Extract, Ocimum Sanctum Leaf Extract, Sodium Lauroyl Lactylate, Sclerotium Gum, Maltodextrin, Ethylhexylglycerin, Proline, Xanthan Gum, Sodium PCA, Sodium Hydroxide, Lecithin, Phenoxyethanol, Citric Acid, Alcohol, Alcohol Denat.

    How does Peptide Squad compare to other peptide serums?

    Most peptide serums on the market fall into one of two camps:

    Single-peptide formulas: They include one or two peptides (usually Matrixyl or copper) at an effective concentration. These work, but they're only addressing one mechanism of aging.

    Peptide cocktails: They list an assortment of different peptides on the label, which sounds impressive—but many lack published clinical studies, and there's often no clear rationale for why those specific peptides were combined. How do they work better together?

    What makes Peptide Squad different: We took a targeted approach: four peptides, each from a different class with a distinct mechanism of action, formulated at clinically-effective concentrations.

    • Signal Peptides (Matrixyl 3000): Stimulate collagen production
    • Neurotransmitter Inhibitors (Argireline): Soften expression lines
    • Carrier Peptides (Copper Tripeptide-1): Deliver copper for collagen synthesis
    • Enzyme Inhibitors (Rice Peptides): Block collagen breakdown

    Each one is backed by published clinical research. Together, they create synergy—attacking aging from multiple angles simultaneously for faster, more comprehensive results than any single peptide can deliver.

    The experience: Unlike many peptide serums that feel heavy or sticky, ours absorbs in seconds. You get serious anti-aging power without the tacky residue or irritation.

    What are the four classes of wrinkle-fighting peptides in Peptide Squad?

    Each class of peptide fights aging through a different mechanism:

    • Signal Peptides (Matrixyl 3000): Tell your skin to build more collagen and elastin
    • Neurotransmitter-Inhibiting Peptides (Argireline): Relax expression lines by reducing muscle contractions
    • Carrier Peptides (Copper Tripeptide-1): Deliver copper to support collagen production and repair
    • Enzyme-Inhibiting Peptides (Rice Peptides): Block enzymes that break down collagen

    By combining all four types, we're addressing aging from multiple angles simultaneously. This creates synergy - the peptides work better together than individually, leading to faster and better results.

    How long would it take to see results?

    First week: Your skin feels smoother, softer, and noticeably plumper to the touch. Makeup glides on without pilling or sliding because this absorbs so cleanly.

    Weeks 4-8: This is the "firming window." Fine lines start to soften, and your skin feels more bouncy when you press on it.

    The long game: This is where peptides really shine. You're not just treating existing damage—you're actively slowing down future aging by supporting your skin's structure every day.

    The goal? In 10 years, look like you've aged only five. Use it daily to keep sending those rebuilding signals to your skin.

    Can I use Peptide Squad with vitamin C and retinoids?

    Yes to both!

    The concern: Some people worry that copper peptides react with Vitamin C, causing oxidation. This is only true for free copper ions.

    Why Peptide Squad is safe: Our copper is bound to GHK peptide (Copper Tripeptide-1), which is a stable complex that naturally occurs in your skin. It's not free copper, so there's no reaction.

    We've tested it: Internal stability tests confirm Peptide Squad doesn't cause oxidation of Vitamin C in Glow Maker.

    How to layer:
    Morning: Vitamin C (Glow Maker) → Peptide Squad → Moisturizer → SPF
    Night: Peptide Squad → Retinoid → Moisturizer

    Both combinations are not only safe; they're complementary. You're getting brightening + collagen building during the day, and cell turnover + structural repair at night.

    Can I use Peptide Squad while pregnant or lactating?

    Yes. The actives in Peptide Squad including peptides, niacinamide, panthenol, hyaluronic acid, natural moisturizing factors, ceramides and jojoba and botanical extracts and actives including allantoin, aloe, green tea, turmeric and polyphenols such as madecassoside (found in CICA) and bisabolol (found in chamomile) are all considered generally safe to use topically during pregnancy and lactation.

    However, it is always advisable to check with your doctor regarding skin care products and ingredients and follow their protocol.